Systemic alpha melanocyte stimulating hormone administration decreases arthritis-induced anorexia and muscle wasting
نویسندگان
چکیده
Ana Belén Gómez-SanMiguel1, Ana Isabel Martín1, Maria Paz Nieto-Bona2, Carmen Fernández-Galaz1, María López-Menduiña1, María Ángeles Villanúa1, Asunción LópezCalderón1. 1 Department of Physiology, Faculty of Medicine, Complutense University of Madrid. 28040 Madrid, Spain. 2 Department of Histology, Faculty of Health Sciences, Rey Juan Carlos University. Av. de Atenas s/n, 28922 Alcorcón, Madrid, Spain
منابع مشابه
Systemic α-melanocyte-stimulating hormone administration decreases arthritis-induced anorexia and muscle wasting.
Rheumatoid cachexia is associated with rheumatoid arthritis and it increases mortality and morbidity. Adjuvant-induced arthritis is an experimental model of rheumatoid arthritis that causes anorexia and muscle wasting. α-Melanocyte-stimulating hormone (α-MSH) has anti-inflammatory actions, and it is able to decrease inflammation in several inflammatory diseases including experimental arthritis....
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BACKGROUND Chronic inflammatory diseases induce cachexia that increases mortality and morbidity of the illness. Adjuvant-induced arthritis is an experimental model of rheumatoid arthritis that is associated with body weight loss and muscle wasting. Alpha-melanocyte stimulating hormone has an anti-inflammatory effect in arthritic rats and decreases muscle wasting. The aim of this work was to elu...
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